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KMID : 0356620060210060567
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Journal of Korean Society of Endocrinology
2006 Volume.21 No. 6 p.567 ~ p.571
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A Case of Cushing`s Disease due to Pituitary Microadenoma Combined with Primary Empty Sella Syndrome
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이윤정
이상열/전숙/오승준/우정택/김성운/김진우/김영설/이병욱/전정원
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Abstract
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An empty sella is defined as a sella which, regardless of its size, is completely or partly filled with cerebrospinal fluid. The endocrine function of primary empty sella syndrome is usually normal, but sometimes this syndrome is associated with complete or partial pituitary insufficiency and rarely hypersecretion of pituitary hormone. Primary empty sella syndrome combined with Cushing's disease has rarely been reported. A 45-years-old woman presented with cushingoid feature. Her urinary cortisol and 17-hydroxycorticosteroid excretion were increased. The results of endocrine function testing were suggestive of Cushing's disease. Sella MRI showed of partially empty sella and pituitary microadenoma. The pituitary microadenoma was removed by the trans-sphenoidal approach. We report here on this case together with a review of the literature.
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KEYWORD
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Cushing`s disease, Empty sella syndrome, Pituitary microadenoma
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